There is no gender difference in the effects of Gui Fu Di Huang Wan. Anyone who meets the drug’s diagnostic and therapeutic categories can take it as prescribed by the doctor. It has the effect of warming and tonifying kidney yang (warming and replenishing kidney yang). Gui Fu Di Huang Wan is clinically indicated for kidney yang deficiency (lack of yang qi in the kidneys) syndrome, which is characterized by lumbar and knee fatigue and coldness, dysuria (irregular urination) or frequent urination, and phlegm-drinking (a pathological product of impaired metabolism of water and fluid) wheezing and coughing. Gui Fu Di Huang Wan is characterized by lumbar and knee fatigue and coldness, dysuria or frequent urination. The adverse effects of the drug have not been clarified. Pregnant women are not allowed to take it. Avoid indigestible food during the period of taking the medicine; it should not be taken by people with fever and cold. Before taking Gui Fu Di Huang Wan, you need to ask your doctor to identify the symptoms and take the medicine under the doctor’s guidance, so as to avoid improper use of medicine and delay the condition.