Gui Shao Di Huang Wan is effective in treating chloasma caused by deficiency of liver and kidney. Gui Shao Di Huang Wan is composed of Angelica sinensis, Paeonia lactiflora, Cornu Cervi Pantotrichum, Radix Rehmanniae Praeparata and other medicines, which is effective in tonifying the liver and kidney, nourishing the yin and blood, and clearing the deficiency heat. The adverse reactions and contraindications of this product are not clear, and patients with cold and fever should not use this drug. Clinically, there are many types of chloasma, such as weak qi and blood, insufficiency of the liver and kidney, etc. Gui Shao Di Huang Wan has certain therapeutic effects on the type of insufficiency of the liver and kidney. If patients need to use the drug, they should be under the guidance of a doctor, and should not use the drug without authorization, so as not to cause adverse consequences.