Patient: Description of the disease (time of onset, main symptoms, hospital visited, etc.): On June 4, 2009, advanced bone metastases from lung cancer were detected, and after 9 chemotherapy and 2 radiotherapy sessions in the hospital, 10 months of taking ERSA, drug resistance developed, the cancer blastocyte index rose, the tumor increased, and the doctor recommended to continue chemotherapy. During the radiotherapy period, the tumor decreased, but the carcinoembryonic cell index continued to increase, and the few months of taking ERSA, the results were good, but now resistance has developed. We don’t know much about intervention, so in order to reduce the patient’s pain and prolong the life span, please ask whether chemotherapy is less painful and more effective or intervention is less painful and more effective. If patients are less sensitive to conventional treatment methods, other methods can be considered. There are also various interventional treatments for lung cancer, including percutaneous puncture tumor (or metastatic lymph nodes) internal irradiation treatment with radioactive particle implantation, percutaneous puncture cryotherapy (or radiofrequency), etc. They also include endotracheal stentoplasty, superior vena cava endoplasty, and percutaneous cement implantation vertebroplasty for spinal bone metastases. These methods are less traumatic for patients and are easy to accept especially for older patients.