Swallowing saliva downward and sore throat are mainly seen clinically in the following types of diseases: first, inflammatory infectious diseases, which are commonly seen clinically as acute purulent tonsillitis, herpes pharyngitis, parapharyngeal space infection, peri-tonsillar abscess, acute epiglottitis, and other related types of diseases. The degree of this pain becomes increasingly severe as the lesion worsens. Anti-inflammatory treatment is clinically effective. The second type, the patient has something in the throat, for example, malignant with malignant ulcers of the tonsils, laryngeal cancer, hypopharyngeal cancer, when the main body of the cancer breaks down and erupts, when the patient swallows there will be a painful sensation in the area of ulceration and rupture. Once the diagnosis is confirmed by clinical examination, surgery and post-operative radiotherapy and chemotherapy are also required. All in all, if a patient has a sore throat when swallowing saliva, it is recommended that the patient go to an ENT clinic for a throat examination to see what kind of disease it is and then proceed with treatment.