Rabies vaccine generally provides effective protection for about six months after the full five doses of vaccination. If you are bitten by a dog or cat within six months after vaccination, you do not need to be re-vaccinated; if you are exposed again within six months to one year, you need a booster vaccination, i.e., one rabies vaccination on day 0 and one on day 3; if you are bitten again more than one year after rabies vaccination, you need to receive the full rabies vaccination again; if you have never received rabies vaccination, you need to receive the full vaccination in time after exposure. If you have never received rabies vaccine, you need to receive the full vaccination after exposure. In addition, regardless of how long you have been vaccinated, the first time you are bitten you should treat the wound by thoroughly washing and rinsing all bites and scratches with 20% soapy water (or other weak alkaline cleanser) alternating with running water at a certain pressure for at least 15 minutes. The wound should then be washed with saline (or water instead) and finally the residual fluid should be absorbed with sterile skimmed cotton to avoid leaving soap and water or detergent in the wound. For deeper wound irrigation, a syringe or high-pressure pulse instrument is used to reach into the deeper part of the wound for irrigation and cleaning, and then alcohol and iodophor are used for local disinfection treatment. Also assess the wound and be sure to administer rabies vaccine, and sometimes rabies immunoglobulin, as soon as there is a break in the skin to achieve a comprehensive defense. There is no effective treatment for rabies, and its attack can only be prevented by rabies vaccination or even rabies immune globulin.