Thrombin is mainly used for various hemostasis and bleeding. In clinical practice, it is mainly applied to bleeding symptoms caused by various diseases or local trauma, and can be used by intramuscular injection and local wet application to achieve the effect of rapid hemostasis. It can make the soluble fibrinogen in the blood turn into insoluble fibrin, and the blood on the surface of the lesion will clot quickly, and the thrombin can also act directly on the blood. It has been used in a wide range of clinical applications, and can be applied to various sites, especially for capillary hemostasis or small vessel hemostasis. It should be noted that in clinical application, a small number of patients may develop allergy after using thrombin and should stop using it immediately.