Children always wake up crying in the middle of the night may be physiological factors, but also may be the manifestation of certain diseases symptoms, such as intestinal spasms, vitamin D deficiency, parasitic infections, etc., should be promptly consulted to identify the cause of the disease. 1. Physiological factors: If the indoor temperature is too high or too low, the child can also appear to sleep at night always wake up and cry, at this time parents should pay attention to the room temperature, timely adjustment can be. 2. Pathologic factors. (1) intestinal spasm: if you don’t pay attention to the warmth of the abdomen or the temperature of the water is cooler when you flush the milk powder, it may cause the baby’s abdomen to catch cold and the intestines to be uncomfortable, which may induce intestinal spasms and produce pain, resulting in the situation that the child always wakes up and cries when he/she sleeps at night. (2) Vitamin D deficiency: Vitamin D deficiency can also lead to children not sleeping soundly at night, always waking up and crying. (3) Parasitic infection: If there is a parasitic infection in the child’s body, the nocturnal activity of the parasite can also lead to the performance of waking up and crying at night. If your child wakes up crying in the middle of the night, it is recommended that you take your child to a doctor to clarify the cause of the illness and provide targeted treatment.