If you have pain in this location, you must consider the possibility of appendicitis, which generally causes pressure pain, rebound pain, abdominal pain, and fever in severe cases. 2. 3. other gastrointestinal reactions, such as acute gastroenteritis, gastrointestinal dysfunction or intestinal cramps. 4. ureteral diseases, such as ureteral stones or urinary tract infections. If it is a ureteral stone, in addition to vague pain, there may be sudden onset of colic, generalized cold sweating or even vomiting, and there may also be symptoms of blood in the urine. In the case of ureteral infection, it is usually accompanied by frequent, urgent and painful urination.