After esophageal mucosal dissection, the mucosa is usually regenerated. The wall of the esophagus is divided into four layers: mucosa, submucosa, muscularis propria, and tunica albuginea. Esophageal mucosal dissection is a procedure in which the mucosa is incised and the submucosal layer of the lesion is peeled off by using an electrosurgical knife or an argon knife about 5 mm outside the marking point at the edge of the lesion, mainly damaging the mucosal layer and the submucosal layer. The epithelium of the esophageal mucosa is a complex flat epithelium, and the basal cells located in the deepest layer of the complex flat epithelium have the ability to proliferate and differentiate, and they can proliferate through mitosis and constantly replenish the cells detached from the surface layer. Therefore, the compound flat epithelium has a strong regenerative repair ability. Esophageal mucosa can be completely regenerated. After esophageal mucosal dissection, it usually takes half a month to one month for the mucosa to regenerate before normal eating. During the recovery period, patients should avoid eating spicy, greasy, cold, hard and other stimulating foods, and it is better to take fluids as the main food, so as to avoid local stimulation, which is not conducive to the recovery of the condition. If discomfort occurs after esophageal mucosa stripping surgery, please consult the hospital in time to avoid delaying the condition.