If a patient wakes up every morning feeling obvious puffiness in the eyelids, the first thing to suspect is the presence of kidney disease, such as acute glomerulonephritis, nephrotic syndrome, chronic glomerulonephritis, etc. You can first go to the nephrology department of the hospital to check the kidney function for preliminary judgment.
In addition, severe heart failure and liver disease may also present with eyelid puffiness that is more pronounced in the early morning and therefore needs to be ruled out with care.