Tetanus shots are generally not recommended the day after drinking alcohol. This is because alcohol is more stimulating to the body, and drinking alcohol can also affect your health. The tetanus vaccine is mainly injected with tetanus immunoglobulin or tetanus antitoxin, and there may be an adverse reaction between the drug and alcohol, which will play a role in prevention, so it is not recommended to drink alcohol before the tetanus vaccine. Moreover, skin test is needed before tetanus vaccination, if drinking alcohol causes an allergic reaction, it may affect the result of skin test and prolong the time of tetanus vaccination, so it is not recommended to take tetanus vaccination after the second day of drinking alcohol. Therefore, it is not recommended to take tetanus vaccine the day after drinking alcohol. If you have already consumed alcohol, it is recommended to wait for a period of time until the alcohol is completely metabolized out of the body before taking tetanus vaccine, and it is necessary to consult a medical professional before vaccination.