Both hydrogen peroxide and leukocyte esterase can determine if there is inflammation in the vagina, so a negative hydrogen peroxide means that there is no significant inflammation in the vagina at that time. If there is inflammation in the vagina, there will be significant leukocytes due to the growth of pathogenic bacteria, and hydrogen peroxide will be secreted, making the hydrogen peroxide test positive. Some tertiary care hospitals also test for sialic acid glycosidase, which is an enzyme specific for bacterial vaginosis, and its activity is proportional to the severity of bacterial vaginosis and is a specific indicator of bacterial vaginosis. However, hydrogen peroxide and leukocyte esterase are not specific indicators of inflammation, so there is no way to determine the type of vaginitis directly from hydrogen peroxide and leukocyte esterase, and a vaginal discharge test is needed to clarify the type of pathogen and guide clinical use.