Can medications treat cerebral palsy? This is a question that has been debated in the industry for a long time, and from the current state of medical development, it is not feasible to rely on drugs to treat cerebral palsy. The human brain has a special anatomical structure, the blood-brain barrier, which prevents general drugs from entering the brain tissue. In addition, brain nerve cells are not renewable, and it is impossible for any drug to revive brain cells that have already died. However, in the early stage of the child (before 1 year old), because the development of the blood-brain barrier is not yet perfect and the permeability is still large, some large molecule neurotrophic factor drugs can still enter the brain tissue, which will have certain efficacy on the growth of nerve cells and nerve fibers as well as the formation and development of nerve myelin. The rehabilitation treatment of cerebral palsy is a comprehensive discipline, and it is not possible to achieve the desired effect by only one single treatment method. In fact, the role of surgery in the treatment of cerebral palsy is not to directly treat the disease itself, but to correct the deformity of the limbs, relieve muscle spasm, prevent joint contracture, and reduce excessive muscle tone, in order to supplement the lack of rehabilitation training or to create favorable conditions and lay a good foundation for rehabilitation training. Therefore, it is a mistake of principle to think that surgical treatment can replace rehabilitation. In recent years, many orthopedic surgeries have been unsatisfactory, largely due to parents’ high expectations of surgery, blindly adopting surgical treatment for children who do not meet the indications for surgery, or thinking that everything is fine after surgery and abandoning systematic functional rehabilitation training. Therefore, surgery for children with cerebral palsy must be strictly controlled by the indications for surgery, carefully selected cases, and the overall design of surgery and postoperative rehabilitation programs according to the principles of surgical treatment, otherwise it will be counterproductive. Conversely, the lack of surgical and orthopedic treatment for rehabilitation will also make it difficult to achieve satisfactory treatment results. In particular, for children with spastic cerebral palsy, which has the highest clinical incidence, it is difficult to achieve satisfactory results if only rehabilitation training is performed. These children should receive the same systematic rehabilitation as other types of children immediately after diagnosis, and then undergo antispastic surgery between the ages of 2.5 and 6 years. If the limb deformity still exists after surgery, the child should continue with orthopedic surgery to address these unrelieved dynamic deformities and pre-existing fixed deformities. Post-operative rehabilitation should be continued and never interrupted as it is necessary to ensure the best treatment outcome.