Hyaluronic acid in the body: In the dermal tissue of human skin, there exists a gel-like substance. It is responsible for storing water, increasing the volume of the skin, keeping it full, plump and elastic with collagen. It is an important part of maintaining healthy and youthful skin, and it is the famous hyaluronic acid. However, as we age, hyaluronic acid will gradually be lost, so that the skin loses its ability to store water, so the human face gradually becomes dull and saggy, and the formation of a small line, the skin begins to age, and people are no longer young. Since hyaluronic acid is lost in the body, can we regenerate it in the skin? Nowadays, the popular facial rejuvenation microplasty can inject hyaluronic acid into the dermis to make up for the lack of hyaluronic acid, so that you can stay young forever. Is the hyaluronic acid in human body eternal? 1. Hyaluronic acid is the most abundant in the human body during the embryonic period, but it will gradually decrease after birth. 2.The retention rate of hyaluronic acid in the body from 0 to 20 years old is 80%~100%. 3.The retention rate of hyaluronic acid in the body is 65% after the age of 25. 4.The retention rate of hyaluronic acid in the body is 45% after the age of 50. 5.Only 25% is left at the age of 60. 6.As we age, the aging of skin is mainly caused by the change of collagen, and the change of collagen is caused by the decrease of hyaluronic acid which has the function of locking water and moisturizing. Hyaluronic acid is also known as hyaluronic acid, which is a kind of large molecule mucopolysaccharide. In 1943, Meyer and Pame discovered hyaluronic acid by extraction from the crystal body of bull’s eye. It is widely found in the intercellular matrix of animal tissues and the vitreous humor of the eye, and is distributed in the vitreous humor of the skin, joint fluid, blood vessels and intercellular matrix of the body. 4.The total amount of hyaluronic acid in human body is not more than 15g, but it is the key to the health and beauty of skin. 5.The average molecular weight of hyaluronic acid sodium salt in human tissue is between 100,000~10 million daltons. 6. The most important biological function is the ability to hold water. What are the characteristics of hyaluronic acid: insoluble, low metabolic rate, high water absorption, high water retention, and not easily transferred between tissues. Hyaluronic acid has occupied a certain position in the soft tissue filler and microplastic application which has been popularly developed in recent years. Specific uses: 1. Combined Botox and hyaluronic acid can be used for forehead, around the eyes, and between the eyebrows wrinkles. 2, lip augmentation, lip lines, lip shape sedan, earlobe augmentation. 3, comprehensive rhinoplasty, rhinoplasty. 4, chin augmentation, jaw asymmetry sedan correction. 5.Filling the dermal depression scars left by trauma or acne. 6.Facial contour correction, temporal collapse filling, eyebrow arch augmentation, cheek augmentation. 7.Improve severe skin dehydration and dryness. However, clinically, the treatment plan should be decided only after professional consultation and overall design by a qualified plastic or cosmetic surgeon. There are some cases that are not suitable for hyaluronic acid injections, such as irregularities on the skin surface caused by some skin lesions that are too shallow, too loose skin, etc. Other more suitable treatment methods should be used. How long does hyaluronic acid last in the body after filling? Hyaluronic acid injected into the body can last from a few months to a few years depending on its cross-linkage, the higher the cross-linkage the longer it lasts, but this is related to the different injection sites and the differences in individual physique. For example, if it is used for lip contouring, it will last shorter than other parts of the face. What is hyaluronidase? Hyaluronidase is also known as vitreonidase, vitragalase, and vitrous acidase. It is an enzyme that hydrolyzes hyaluronic acid (hyaluronic acid is a component of the tissue matrix that has the effect of limiting the diffusion of water and other extracellular substances) and is used in the human body to temporarily reduce the viscosity of the intercellular matrix, which accelerates the diffusion of locally accumulated exudate or blood and facilitates absorption, and is an important drug diffusing agent. It is used clinically as a drug penetrating agent to promote the absorption of drugs and the dissipation of local edema or hematoma after surgery and trauma.