Waking up with neck and shoulder pain can be caused by myofasciitis of the neck and shoulder, frozen shoulder, cervical spondylosis and so on. 1. Neck and shoulder myofasciitis: it may be caused by incorrect sleeping posture, high pillow, always maintaining a posture, etc. It may lead to neck and shoulder stiffness for a long time, causing muscle spasm and strain, which will cause the phenomenon of waking up with neck pain and shoulder pain. 2. Frozen shoulder: it may be due to the improper treatment of acute contusion of the shoulder, long-term over-activity, poor posture and other factors, resulting in frozen shoulder, and then the phenomenon of waking up with neck pain and shoulder pain. 3. cervical spondylosis: may be due to cervical spine long-term strain, osteophytes, intervertebral disc prolapse, ligament thickening, etc., resulting in cervical spondylosis, will wake up with neck pain shoulder pain phenomenon. Waking up with neck pain and shoulder pain may also have other reasons, it is recommended that patients go to the regular hospital in a timely manner, improve the relevant examination, clear the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.