Hydroquinone cream is a topical cream for the treatment of hyperpigmentation, and its composition is mainly hydroquinone, which is the classic medication for hyperpigmentation. Hydroquinone cream has more side effects. If hydroquinone cream is treated for about two months and there is no lightening of pigmentation or disappearance of pigmentation, it is not recommended to continue to apply at this time. If hydroquinone cream is applied for a long time, it may cause damage to the skin. It may cause skin allergy, such as local itching, redness, swelling, pain, burning sensation, or even blistering. Moreover, after applying hydroquinone cream, freckles may appear if repeatedly exposed to sunlight. And because it contains heavy metal ingredients, it is toxic to liver, so it should not be applied for a long time. The production of facial pigmentation spots is related to genetic susceptibility, ultraviolet radiation, pregnancy, endocrine diseases and cosmetics, etc. For getting rid of facial pigmentation spots, besides using hydroquinone cream, you should also do a good job of daily care, pay more attention to sun protection, apply sunscreen products and eat more vegetables and fruits. You should also take Chinese herbal medicine that can help you to remove the liver and spleen, nourish the blood and remove the spots, and use herbal masks that have the effect of removing spots and whitening.