Infiltration generally does not mean spreading, but once infiltration occurs, the cancer will easily continue to develop and lead to spreading. Infiltration generally refers to the cancer lesion breaks through the basement membrane and invades the submucosal layer and muscle layer, etc. According to the depth of infiltration, it is clinically divided into early-stage infiltrating cancer and late-stage infiltrating cancer. Proliferation generally refers to the spread of cancer lesions through direct spread, lymphatic channel and blood circulation, and at this time, the disease is often in the middle or late stage. Once a clinical cancer lesion develops from carcinoma in situ to invasive cancer, it means that the cancer lesion can easily spread through local spread, lymphatic channel and blood circulation. Patients are advised to take active treatment to avoid the spread of cancer.