Xiao Li’s mother has ovarian cancer, Xiao Li and her boyfriend Xiao Wang are already talking about marriage, Xiao Wang’s mother heard about it and firmly opposed the marriage, saying that ovarian cancer runs in the family. The two people were scared to hear about it and wondered if it was true that the ovarian cancer would be passed on to the next generation. Xiao Wang’s mother’s fears are justified because family history is an important factor in the development of ovarian cancer and ovarian cancer is hereditary. In order to correctly estimate the population at risk for ovarian cancer, some people have classified ovarian cancer into three categories from a genetic epidemiological point of view: Category I, sporadic ovarian cancer: refers to ovarian cancer families in the second generation of blood relatives (including siblings, children and both grandparents), no ovarian cancer or other tumors related to it is found. The second category, familial ovarian cancer, refers to a family with two or more blood relatives of one or two generations who have ovarian cancer together. The third type, hereditary ovarian cancer, refers specifically to families with aggregated ovarian cancer that exhibit autosomal dominant inheritance and may have other types of cancer as well. This type is often referred to as hereditary ovarian cancer syndrome. Hereditary ovarian cancer syndrome is characterized by an early age of onset. While the average age of onset of ovarian cancer in general is 59 years, the average age of onset of this hereditary ovarian cancer is 52 years. Family history of ovarian cancer is a high-risk factor. In fact, family history of endometrial cancer, breast cancer, and bowel cancer are also the same genetic defects as ovarian, which are also high-risk factors for ovarian cancer, and it is completely necessary for women with family history of these cancers to be more vigilant and should pay attention to regular medical checkups at hospitals. However, women with a family history of these cancers need not be afraid. In fact, hereditary ovarian cancer is relatively rare. About 7% of ovarian cancer patients have a positive family history, and less than 1% of the total number of ovarian cancer patients actually have hereditary ovarian cancer. With the rapid development of technology, especially genetic testing technology, ovarian cancer genetic testing is a new development direction for early prevention of ovarian cancer in the future. BRCA1 mutation increases a woman’s risk of developing ovarian cancer by 50% and breast cancer by 87%. Therefore, healthy family members with a family history of ovarian cancer should be screened for their own mutations. For women who have completed childbirth and are between the ages of 35 and 40, they may consider prophylactic bilateral salpingo-oophorectomy; for those who have not undergone bilateral salpingo-oophorectomy, they may consider annual CA-125 and vaginal ultrasound screening starting at the age of 30-35. Screening.