SLE is a chronic autoimmune disease with multisystem damage, mostly in women between the ages of fifteen and forty. 1. Causal factors: The causes of SLE include genes, endocrine abnormalities, environmental influences, etc. It has been found that 0.4% to 0.5% of patients have a relative suffering from lupus erythematosus or other immune diseases. Sex hormones have been studied to have an effect on the triggering of lupus erythematosus. Sunlight can trigger or aggravate lupus erythematosus. 2. Symptoms: Erythema is a common and more obvious symptom of this disease. Most patients will have erythema. They are mainly on the parts exposed to the sun. In the early stage, these erythematous spots are not large, while in the middle and late stages, these erythematous spots will gradually expand. In addition, patients may also show various symptoms such as kidney, cardiovascular system, respiratory system, digestive system, blood system and nervous system. 3.Treatment: The treatment of lupus erythematosus needs to be personalized and can be treated with glucocorticoids, immunosuppressants, immunoglobulins and other drugs according to the patient’s condition. The medication should be taken according to medical advice and the dosage of medication should not be changed without authorization. Therefore, SLE is an immune disease with complex etiology and diverse clinical manifestations.