The prefrontal lobe of the brain is a part of the human brain tissue, and its main function is to be responsible for thinking and calculating, and it is directly related to human emotion and personality, after the frontal lobe lesion, the patient appears emotional indifference, depression, etc., and cognitive function is reduced. The frontal lobe is the most advanced part of brain development, including motor area and premotor area, and the frontal lobe mainly refers to the part before the central sulcus. The cause can be determined by CT or MRI of the head. For treatment, active treatment is given to the cause, and acupuncture and massage are also used to improve the emotional indifference after frontal lobe damage.