Thyroid nodules seldom cause wasting, but there are 2 special cases: 1) the nodules belong to high power adenomas, which cause hyperthyroidism and lead to wasting; 2) malignant nodules develop into thyroid cancer, and the cancer spreads rapidly, sucking up the normal energy and nutrients of human beings and leading to wasting. The former is more common, high-power adenomas cause hyperthyroidism in about 20% of such cases, generally diagnosed as thyroid adenomas are taken to surgical resection, to avoid causing malignant changes or hyperthyroidism, once caused by hyperthyroidism, due to the increase in thyroxine secretion will lead to accelerated metabolism, so that people lose weight quickly, accompanied by other symptoms of the nervous central system. Malignant tumors are more serious, and when they lead to weight loss, they are usually combined with extensive metastases, and the cancerous foci themselves are very large, so that they can take in the nutrients normally supplied to the person, so either of them needs early surgical treatment.