Tubuloadenomas of the transverse colon are usually eligible for the third booster shot. Tubular adenomas of the transverse colon are benign tumors of the intestinal mucosa of the transverse colon, mostly caused by inflammatory stimulation leading to local hyperplasia, and may be associated with symptoms such as diarrhea and abdominal pain. This type of tubular adenoma usually recovers well after colonoscopic resection, so it is possible to get the third booster shot. However, if the tubular adenomas are multiple, it is best to take a break of about half a month to one month before receiving the third booster shot after the colonoscopy. Generally, the third booster vaccine does not have a significant effect on tubular adenoma disease. Anyone of the appropriate age group should receive the booster vaccination. If there is any underlying disease, it is recommended to consult the doctor at the vaccination center.