Patients with anal fissures usually do not need to take anti-inflammatory drugs. For early mild anal fissures, topical application of erythromycin ointment, Ma Yinglong hemorrhoid cream, mupirocin ointment, together with the use of Anal Tai suppositories, Ma Yinglong hemorrhoid suppositories or Puji hemorrhoid suppositories, can play a role in promoting wound healing. For anal fissure with more severe pain, it needs to be treated with diclofenac sodium suppositories for pain relief. For anal fissures with severe jet bleeding and heavy bleeding, oral hemostatic granules or Zicang capsules should be taken to stop the bleeding. But for patients with anal fissure accompanied by infection, oral anti-inflammatory drugs such as cephalosporins and metronidazole are needed for comprehensive treatment, and at the same time, Xinhuang tablets or small septic cream can be used to clear heat and detoxify the toxin.