What is facial hormone dependent dermatitis

  Facial glucocorticoid dermatitis is a chronic skin disease caused by the prolonged topical use of steroid hormones on the face, with clinical manifestations such as facial capillary dilation, erythema, papules, dryness and skin atrophy. In recent years, due to improper use of steroid hormone drugs, abuse of topical glucocorticoids and some women’s blind pursuit of whitening and rejuvenation, long-term use of substandard cosmetics, facial hormone dependent dermatitis has become a common dermatological disease. It has now become the fifth most common dermatological disease after eczema, psoriasis, acne and urticaria. It is also difficult to treat, affects the appearance, brings inconvenience to patients’ life and work, and causes certain psychological pressure.  The long-term repeated external use of glucocorticoids inhibits the proliferation and differentiation of epidermal cells, resulting in a decrease in keratinocytes and abnormal function, which destroys the epidermal permeability barrier and reduces the keratin water content. This induces a cascade of inflammatory reactions. These include various cytokines produced by keratinocytes, which diffuse to the dermis, further inducing dermal inflammatory reactions, due to the destruction of the epidermal barrier function, the sensitivity to external physical and chemical factors such as light, heat, detergents and other external stimuli increase, further stimulating the occurrence of dermatitis.  1. Wrong choice of indications: Some people misinterpret the “anti-inflammatory” effect of corticosteroids as the anti-inflammatory and antibacterial effect of antibiotics and use them repeatedly and inappropriately for a long time. For example, common skin diseases such as acne (youth acne) and seborrheic dermatitis. Corticosteroids have the anti-allergic effect of inhibiting immune response, and can reduce congestion and edema after topical application, so that the degree of itching and the inflammatory reaction of certain skin damage can be temporarily relieved and subside, and many people lack understanding of the scope of application of hormones and adverse reactions and use them for a long time, leading to adverse consequences.  2, the confusion of the beauty market and cosmetic abuse: with the rapid development of the beauty industry and the fierce competition of beauty salons, some beauty salons will hormones mixed into skin rejuvenation, whitening cosmetics, so that many consumers thirsty for beauty and skin care, in the long-term application of their so-called “special effects of skin rejuvenation, whitening cosmetics” after dependence, and lead to Hormone-dependent dermatitis.  Clinical manifestations 1. When highly effective corticosteroids are applied externally to the same area for more than 3 weeks, secondary symptoms such as erythema, papules, dry flaking, atrophy, atrophy lines, capillary dilation, purpura, acne, abnormal pigmentation, rosacea-like dermatitis, perioral dermatitis, photoallergy, hirsutism, ringworm that is not easily identifiable, ichthyosis-like changes, etc. appear on the skin.  2.After applying the above hormone drugs, although the original disease can be rapidly improved; once the drug is stopped, within 1-2 days, significant erythema, papules, chancroid, desquamation, small pustules, itching and tenderness of the skin at the drug site occur. When the drug is used again, the above signs and symptoms will quickly subside, such as the discontinuation, dermatitis symptoms and quickly again, and gradually aggravated, the dependence on hormones is more obvious.  3. There is obvious local conscious itching or burning sensation.