Fifty-year-old man sexual function decline may be physiological factors, mental and psychological stress, high blood pressure and diabetes, kidney disease and other factors, causative factors are different, to take the treatment is not the same, including the adjustment of living and eating habits, improve the psychological state, the existence of disease factors, should also be reasonable medication for treatment. 1. Physiological factors: androgen levels in the body of a fifty-year-old man may gradually decrease, which will have an impact on sexual function, causing a decline in sexual function, but it will not have too much impact on the quality of sexual life, generally do not need special treatment. 2. Excessive mental and psychological stress: excessive mental and psychological stress or physical fatigue in work and life can also cause a decline in sexual function, should adjust the psychological state, avoid excessive psychological stress, and avoid staying up too late, more rest, more physical exercise, to improve their physical fitness, and promote the gradual recovery of sexual function. 3. Hypertension and diabetes: For hypertension and diabetes, antihypertensive and hypoglycemic drugs should be used for treatment, such as nifedipine extended-release tablets, metformin, etc., to strictly control the blood pressure and blood glucose, to avoid recurrence of the disease. 4. Kidney disease: for example, nephrotic syndrome, after diagnosis, medication can be administered, such as cyclophosphamide, spironolactone, etc. For particularly severe nephrotic syndrome, kidney transplantation can be considered for patients who are in a position to do so. In the process of treatment, must follow the doctor’s guidance, safe and reasonable use of medication therapy, do not use drugs indiscriminately.