Diffuse congestion and edema of the descending colon means inflammation of the descending colon leading to diffuse congestion and edema of the colon. It may be caused by bacteria, protozoa, environmental and genetic factors, intestinal microecological abnormalities and so on. Patients are advised to undergo medication, surgery, etc. in a timely manner to avoid delays. Diffuse congestion and edema of the descending colon is a manifestation of colitis, which is mainly due to bacteria, protozoa and other infections, and may also be related to environmental and genetic factors, intestinal microecological abnormalities and so on. Patients may have diarrhea, abdominal pain, mucus stool, pus and blood stool, urgency and heaviness, constipation and other symptoms. Patients are advised to take active treatment to avoid complications such as ulcerative colitis and Crohn’s disease. Commonly used therapeutic drugs include mesalazine, olsalazine, prednisone, etc. Antibiotics such as ciprofloxacin, metronidazole, diclofenac, etc. can also be used for treatment. If combined with intestinal obstruction, intestinal perforation, severe intestinal necrosis and other patients can be surgical treatment. Diffuse congestion and edema of the descending colon, it is recommended that patients go to the hospital in time for treatment, and if you need to use drugs, you need to use them under the guidance of a doctor.