Hippocampal atrophy is mainly examined by MRI. Hippocampal atrophy can show a reduction in hippocampal volume on MRI, and in severe cases, hawk-like changes can be accompanied by temporal lobe atrophy and temporal horn enlargement, which is especially obvious on coronal imaging of MRI. Hippocampal atrophy is most commonly seen in older adults over the age of 60, primarily causing memory loss, and as the atrophy progresses, there may be a gradual overall decline in cognitive function, including memory, language, reaction, executive, computational, and visuospatial abilities. Hippocampal atrophy is mostly seen in patients with Alzheimer’s disease. There is no effective cure for hippocampal atrophy, but only symptomatic treatment with drugs to improve cognitive function, commonly used drugs include donepezil hydrochloride and memantine.