In the February 2015 issue of Obstetrics & Gynecology, the American College of Obstetricians and Gynecologists Committee suggests that “removal of the fallopian tubes may prevent ovarian cancer. The Obstetricians and Gynecologists Association concluded that performing a tubectomy or tubal sterilization at the time of hysterectomy appears to be safe without increased complications compared to hysterectomy or tubal ligation alone. Counseling on the risks and benefits of tubectomy for women undergoing routine pelvic surgery should include an informed consent form for both oophorectomy and bilateral tubectomy. Ovarian cancer has the highest mortality rate among gynecologic cancers; it has risen to fifth place in the ranking of women’s cancer mortality rates now. Survival rates for ovarian cancer have not improved significantly in the last 50 years. Considerations for tubectomy to prevent ovarian cancer: 1. Surgeons should discuss the potential benefits of tubectomy based on the population risk ratio for ovarian cancer among women. 2. Physicians should inform women considering laparoscopic sterilization that bilateral tubectomy can provide effective contraception and should point out that this procedure can also prevent tubal torsion as a disease. 3. For some patients, prophylactic salpingo-oophorectomy may prevent ovarian cancer. 4, More randomized controlled trials are needed to validate the use of tubectomy for the prevention of ovarian cancer. The committee calls on surgeons to use minimally invasive techniques. At this time, the benefits of tubectomy should not influence decisions about which method to use for hysterectomy sterilization. For example, the committee recommends that surgeons not switch from vaginal hysterectomy to laparoscopic hysterectomy simply to perform a vasectomy. The committee concluded that approximately 75% of ovarian cancers and 90% of deaths from ovarian cancer are caused by epithelial ovarian cancer, in contrast to the conventional view. In contrast to the traditional view that epithelial ovarian cancer originates in a small part of the ovary, the latest research suggests that epithelial ovarian cancer originates in the fallopian tubes and part of the endometrium. Studies also suggest that tubal ligation has a preventive effect on clear cell carcinoma of the endometrium. Based on current opinion regarding ovarian carcinogenesis, the committee believes that removal of the fallopian tubes alone, leaving the ovaries intact, may be more effective in preventing cancer than oophorectomy and bilateral tubal and oophorectomy. The latter leads to earlier menopause, increased risk of cardiovascular disease, osteoporosis, and cognitive impairment and was found in the Nurses’ Health Study and is associated with an increased risk of all-cause and cancer death exclusively.