Chronic rhinos_sinusitis is defined as recurrent nasal congestion, runny nose and headache for more than 8 weeks. It usually comes from acute rhinosinusitis, and if acute rhinosinusitis is not treated thoroughly, chronic rhinosinusitis can easily develop. Acute rhinosinusitis is usually the result of the common term “cold”. Chronic rhinosinusitis can be divided into those with polyps and those without. The main treatment for those with polyps is surgery, and glucocorticoids can be given orally and nasal spray before surgery to reduce the size of the polyps and reduce the edema of the nasal mucosa, which is conducive to post-operative recovery. The treatment of chronic rhinosinusitis (without polyps) should be preferred to pharmacotherapy, according to the characteristics of the mucous membrane of the nasal cavity, we choose three kinds of drug therapy: 1, macrolide antibacterial agents such as clarithromycin, roxithromycin. 2, mucus pro-discharge agents such as Ceno. 3.Glucocorticoid nasal spray such as Burkitt Sodium, Reynocort, Nesuna, Cochlear. 4.Rinsing of nasal cavity: rinse the nasal cavity with saline 2-3 times a day, 100 ML each time. three kinds of drugs continue to use 1-3 months, during the use of drugs to regularly check liver and kidney function. In case of no effect after 1-3 months of treatment with medication, surgical treatment can be adopted. Functional nasal endoscopy is a minimally invasive surgery that opens the diseased sinus opening and preserves the normal mucosa of the nasal cavity, which is conducive to the recovery of the physiological function of the nasal mucosa. Chronic nasal-sinusitis postoperative care is very important, postoperative hospitalization for 3-4 days, intravenous administration of cephalosporin antimicrobials for three days after surgery, and self-rinse nasal cavity with saline 2-3 times a day for one week after surgery, using the above three drugs for the same period. It is not advisable to use instruments such as forceps for the first time, but only to clean the nasal cavity with secretions and blood crusts by suction, and to clean the vesicles and granules during the second week of microscopic examination, and to start mucosal epithelialization in the third week. Local application of erythromycin ointment to the nasal cavity after each cleaning is recommended to promote the epithelialization of the mucosa. The patient’s own care is very important, with daily rinsing of the nasal cavity and timely administration of medication. The surgical treatment of chronic rhinosinusitis is only part of the treatment, the later medication and care are more important, I hope all patients can realize this seriously.