In the process of treating asthma patients, some patients often ask: “Doctor, is it true that asthma will not attack if we actively exercise and strengthen our resistance? Let’s try to analyze the possible sources of this view: 1. Advertising of health care products: Many health care products are advertised to enhance the body’s resistance, so that people can get less disease or even no disease. Over time, this has instilled in people the view that “almost all diseases are caused by lowered resistance, and strengthening resistance can prevent or reduce diseases”; 2. the life experience of asthma patients: many patients’ attacks are often secondary to a “cold and flu “Therefore, it is natural for patients to conclude: “If I don’t catch a cold, I won’t have an asthma attack. It is because of lack of exercise and poor resistance”. Is this really the case? It is true that proper physical exercise can enhance the body’s ability to resist foreign infectious agents, commonly known as “resistance building”. However, the onset of many diseases is not related to infection, such as: high blood pressure, coronary heart disease, diabetes, etc.. Asthma is an allergic disease, and relying solely on exercise and resistance building is not a substitute for medication. Having said that, many of my friends may retort to me: “Why did my asthma attacks come after a cold these few times? Why do you say that asthma has nothing to do with infection?” We can analyze this topic a little bit. Is it always the “cold” that triggers an asthma attack? The formal medical name for a cold is “acute upper respiratory tract infection”, which is an inflammation of the upper respiratory tract caused by a number of viruses, bacteria or even atypical pathogens, with the main scope of the lesions being limited to the nasal and pharyngeal cavities. The main symptoms are “nasal congestion, runny nose, dry mouth, sore throat” and other symptoms, which can be cured within a week with or without medical treatment. There is a group of diseases that are very similar to colds in terms of symptoms, patients also have severe runny nose and sneezing symptoms, which usually last for more than a week, and in severe cases, combined with itching around the nose and eyes, and even lead to persistent cough. Allergic rhinitis, like asthma, is an allergic inflammatory disease that usually strikes in the spring and fall when environmental pollen concentrations are high, and the rate of allergic rhinitis combined with asthma is as high as 80 percent. This may be part of the reason why many patients think that “asthma is secondary to cold”. After all of the above, it is not true that asthma has nothing to do with infection at all. The relationship between infection and asthma can be discussed from two aspects: infection and asthma onset and infection and acute asthma attack. First, studies have shown that respiratory infections, especially viral infections, are closely related to the development of asthma. In particular, viral infections in childhood often cause the onset of asthma, probably by stimulating the body to produce specific IgE, which results in an IgE-mediated acute allergic reaction. Whether bacterial infections cause the onset of asthma is debated. Secondly, most acute attacks in patients with allergic asthma are related to exposure to allergens (e.g., dust mites, pollen, etc.), but as the disease progresses, infection plays an increasing role in acute attacks in some patients, especially in middle-aged and elderly asthmatic patients. Therefore, for this group of patients, enhancing resistance and reducing infection attacks can indeed indirectly reduce acute asthma attacks. In conclusion, for those middle-aged, elderly and young asthma patients who are prone to asthma attacks induced by infections, appropriate physical exercise can enhance body resistance and indirectly reduce acute asthma attacks with positive significance, but simply enhancing resistance is not a substitute for formal drug therapy. For those patients whose asthma attacks are mostly triggered by allergic factors, the one-sided emphasis on strengthening resistance and ignoring the role of medication is one-sided and harmful.