Acute pancreatitis can cause diabetes, and the pancreas is an important gland in the body. The pancreas has both endocrine and exocrine functions. The exocrine function of the pancreas is to secrete a variety of digestive enzymes to facilitate the digestion and absorption of food. The endocrine function of the pancreas is to secrete insulin from the beta cells of the pancreas, which is the only hypoglycemic hormone in the body, and diabetes occurs when insulin secretion is insufficient or resistant to action for various reasons. When pancreatitis, especially severe pancreatitis, causes damage to islet function and leads to the development of diabetes. In relatively mild acute simple pancreatitis, the initial attack does not necessarily lead to diabetes. However, if acute pancreatitis recurs or if chronic pancreatitis develops, resulting in the proliferation of fibrous tissue in the pancreas, it can affect islet beta cell function and predispose to diabetes.