Benzafibrate Effects and Side Effects

Benzafibrate is a lipid-modifying drug whose main effect is to treat hypertriglyceridemia, hypercholesterolemia, and mixed hyperlipidemia. Side effects include dyspepsia, anorexia, headache, cholelithiasis or myositis. There are two mechanisms for the hypolipidemic effect of benzafibrate, one is to increase the activity of lipoprotein lipase and hepatic lipase, to promote the catabolism of very low density lipoprotein, so that the level of blood triglyceride is reduced. The second is to reduce the secretion of very low density lipoprotein. Benzafibrate lowers blood LDL and cholesterol, lowers blood triglycerides, raises HDL, and lowers blood fibrinogen. Side effects of this drug commonly include gastrointestinal discomfort, such as dyspepsia, anorexia, nausea and vomiting; rarely, headache, dizziness, fatigue, impotence, anemia, leukopenia; and occasionally, cholelithiasis or myositis, myalgia, fatigue, and increased blood aminotransferases. In addition, it is prohibited for patients who are allergic to benzabepet, prohibited for patients with gallbladder disease, cholelithiasis, hepatic insufficiency, primary biliary cirrhosis, and severe renal insufficiency, not recommended for pregnant women, and contraindicated for breastfeeding women and children. If you need to use Benzafibrate, it is recommended to consult a professional doctor, follow the doctor’s instructions to standardize the treatment, not blindly use the drug on their own.