High LDL is generally related to genetic factors, irrational diet, lack of exercise, excessive mental stress, etc. It is also related to other diseases and medications. 1. Genetic factors: High LDL, if it is a primary dyslipidemia, is mainly related to genetic defects, and this kind of dyslipidemia caused by genetic defects has the characteristics of family inheritance. 2. Dietary factors: Dietary factors are mainly eating too much greasy food, especially pork, beef and mutton with high content of saturated fatty acid, pork, beef and mutton offal, pork, beef and mutton oil, etc., which will induce LDL elevation. 3. Lack of exercise: prolonged sedentary inactivity is likely to lead to calorie accumulation and storage of excess calories as fat, causing high triglycerides. 4. Excessive mental stress: Due to high mental stress and depression, many people tend to eat a lot of fatty foods, drink alcohol and smoke to help relieve tension, which in turn induces high LDL. 5. Disease factors: Hypothyroidism, nephrotic syndrome, Cushing’s syndrome and other diseases can lead to abnormal lipid metabolism, which may trigger secondary dyslipidemia and lead to elevated LDL. 6. Drug factors: when taking diuretics, glucocorticoids and other drugs, may also lead to abnormal lipid metabolism, triggering elevated LDL. Once the LDL is high, it will induce atherosclerosis and increase the risk of cardiovascular and cerebrovascular diseases, so you need to consult a doctor in a timely manner and strictly follow the doctor’s instructions for examination and treatment.