The stomach cramps and diarrhea is considered to be caused by acute gastroenteritis, inflammatory bowel disease and other diseases, it is recommended that targeted treatment under the guidance of the doctor, such as drug therapy, surgical treatment. 1. Acute gastroenteritis: if the bacterial infection caused by acute gastroenteritis can be prescribed by the use of levofloxacin, ciprofloxacin anti-infection treatment, if the diarrhea symptoms are serious need to use loperamide to stop the diarrhea, accompanied by symptoms of dehydration need to be taken orally or intravenously rehydration. 2. Inflammatory bowel disease: you can use Liuzosulfapyridine, mesalazine and other drugs for the treatment of mildly and moderately active patients, dexamethasone can control the progress of the disease, if there is a perforation of the bowel need to be operated. 3. Ischemic enteropathy: the intestinal wall is ischemic, hypoxic, and eventually infarction occurs. Patients may have sudden spasmodic pain in the left lower abdomen, accompanied by stool and blood in the stool, and also accompanied by diarrhea. Intravenous rehydration should be used to maintain the fluid balance in the body, and surgery should be performed if necessary. 4. Intestinal tumor: colic and diarrhea can also occur, diagnosed intestinal tumor should be treated with surgery in time, or combined with radiotherapy and chemotherapy according to the needs of the condition. In case of stomach cramps and diarrhea, it is recommended to go to the hospital and ask the doctor to make a judgment and clarify the cause of the disease.