Engelezin tablets can be taken for a long time, but should be under the guidance of a physician, according to the patient’s blood glucose control, a comprehensive assessment of its glucose-lowering effect, so as to adjust the dose and time of taking, avoid unauthorized discontinuation of the drug and change the dose. The mechanism of action of Engelezin Tablets is mainly through the inhibition of glucose reabsorption in renal tubules and the promotion of glucose excretion from urine, so as to achieve the effect of lowering blood glucose. It also has the effect of reducing body weight, lowering uric acid, blood lipids, blood pressure, and can reduce the mortality rate of type 2 diabetes mellitus patients with combined cardiovascular system diseases. Engeletin tablets can be applied alone or in combination with other hypoglycemic drugs with good effect, but it is not recommended to be used for type 1 diabetes or for the treatment of diabetic ketoacidosis. Engeletin is contraindicated in individuals with a history of severe hypersensitivity reactions to engeletin, severe renal impairment, end-stage renal disease, or dialysis. Common adverse reactions include hypersensitivity, hypoglycemia, ketoacidosis and urinary tract infections. Therefore, Engeletin tablets should be used reasonably under the guidance of a physician, and attention should be paid to drinking more water and monitoring blood glucose to prevent urinary tract infection and hypoglycemia during the use of the drug. When adverse reactions occur, you should go to the hospital in time to avoid delays in diagnosis and treatment.