Leukoaraiosis, also known as Behçet’s disease and oro-ocular-genital triad, is a chronic disease that affects both men and women and is characterized by oral mucosal ulcers, ophthalmitis, and skin damage, and can involve multiple systems. The disease alternates between recurrent episodes and remission. The cause of the disease is not particularly clear and may be related to genetics and pathogenic infections. Almost all patients develop recurrent, painful oral ulcers, which can occur anywhere in the mouth, preferably on the tongue, buccal mucosa, gums, and palate; some patients may develop genital ulcers, often on the vulva, vagina, perianal area, scrotum, and penis; patients with ophthalmia may present with blurred vision Patients with ophthalmia may show symptoms such as blurred vision, decreased vision, eye congestion, eye pain, photophobia and tearing, foreign body sensation, and headache. The incidence of skin lesions is high and the manifestations are varied. They may appear as erythema nodosum, acne-like folliculitis, and other manifestations, with pale, dark red or purple subcutaneous nodules or papular pustules that are painful and painful to the senses. Leukoaraiosis may involve all systems of the body, involving the nervous system damage may appear headache, epilepsy, aseptic meningitis, hemiparesis, sensory impairment or numbness and weakness of the limbs; appearing gastrointestinal tract damage may manifest as ulcers of the entire gastrointestinal tract from the mouth to the anus; involving the cardiovascular system may appear vasculitis as well as venous thrombosis, myocardial infarction, etc., which is the main cause of death and disability. However, most patients have a good prognosis, while a small number of patients may suffer from blindness, hemiplegia, or even death.