There are no symptoms associated with portal hypertension in the compensated phase of cirrhosis, but elevated portal pressure and mild to moderate enlargement of the spleen may be present on imaging. Patients with compensated cirrhosis do not have specific manifestations and may have dyspeptic symptoms, such as poor appetite, abdominal discomfort, and fatigue. The further development of portal hypertension can be delayed if the cirrhosis is treated with active control of the primary disease, liver preservation and antifibrosis during the compensated stage. With the progression of lesions, liver cirrhosis enters into the decompensated stage, and obvious symptoms related to portal hypertension will appear, such as bleeding from fundic esophageal varices leading to vomiting blood, black stool, ascites in liver cirrhosis, hypersplenism leading to platelet and leukocyte decrease, proliferative anemia, etc. The condition of patients in the decompensated stage is critical, which may jeopardize the patient’s life. It is recommended that patients with cirrhosis should actively standardize the treatment to avoid continuous aggravation of the condition, which may threaten patients’ lives.