Severe heterogeneous hyperplasia is not cancer yet, but it has a high possibility of developing into cancer, so it needs to be treated as early as possible. Heterogeneous hyperplasia is a pathological term, which means that the cell shape under microscope has deviated from the normal appearance and developed into heterogeneity. Heterogeneity often shows that the cell shape is not as regular as normal, but oddly shaped, the cell arrangement is not neat and uniform, but very disorganized, and the cell size is not uniform, but unequal. According to the degree and scope of heterozygosis, it is divided into mild, moderate and severe. Severe heterozygosis is the form closest to cancer, which is generally considered as precancerous lesion and has lost the possibility of returning to normal form, and because severe heterozygosis is irreversibly developing towards cancer, it needs to be treated as early as possible to interrupt its cancerous process.