I. Genetic factors Parents or a family history of diabetes are susceptible to the disease, and the disease will develop only when environmental factors are present. Environmental factors 1, viral infection; 2, obesity; 3, high sugar, high fat, high protein food too much; 4, pregnancy; 5, hypertensive disease; 6, usually less physical activity; 7, long-term use of diuretics and hormonal drugs; 8, emotional fluctuations: mental tension, depression pessimism. Vitamin and micronutrient deficiency 1, lack of VB6 and Mg → urinary yellow uric acid (↑), VB6 involved in amino acid metabolism, Mg ↓ insulin resistance; 2, saturated fatty acids; 3, high protein and high calorie diet will ↑ VB6 demand; 4, a variety of drugs will make yellow uric acid rise, such as: penicillin.