After PICC placement, it is best if the tip of the catheter can be seen on the chest radiograph between the 5th and 6th rib space, which is in the middle and lower third of the superior vena cava, and near the right atrium. The catheter tip is placed in the central vein. Once the drugs are infused into the central vein, they are quickly carried throughout the body by the blood flow and are not likely to cause phlebitis or excessive complications. If the tube is too shallow, there is a risk of slippage during the procedure. If the tube is placed too deep, it may enter the right atrium and the heart, which may lead to risky situations.