The instruction does not mention that taking Gui Spleen Pill will cause constipation. Constipation occurring during taking Gui Spleen Pill is considered to be related to dietary factors, insufficient exercise and organic lesions. Gui Spleen Pill is a commonly used Chinese medicine in clinical practice, which is a combination of medicines such as sour jujube kernel, fried Atractylodes macrocephala, Radix et Rhizoma Ginseng and Poria. It has the effects of nourishing blood and tranquilizing the mind (stabilizing the mind and soothing the emotions by nourishing the blood), benefiting qi and strengthening the spleen (regulating the qi of the spleen and stomach). It can be used for deficiency of the heart and spleen, shortness of breath and palpitation, insomnia and excessive dreaming, dizziness and lightheadedness, tiredness and weakness of limbs, and loss of appetite. There are more causes of constipation, such as drinking water, eating crude fiber food, too little fresh vegetables and fruits, prolonged sedentary, intestinal lumen tumors, congenital megacolon, endorectal intussusception, hemorrhoids, anal fissure and other diseases, which can cause constipation. If it occurs during the time of taking Rejuvenate Pills, it can easily be mistaken as caused by taking Rejuvenate Pills. This product may cause gastrointestinal discomfort and skin rash, contraindications are not clear, pay attention to the use of avoid indigestible food; cold and fever patients should not be taken; there is thirst, yellow urine, constipation and other manifestations of internal heat should not be taken; take the drug for 4 weeks without symptomatic relief, you should go to the hospital for consultation. Difficulty in defecation, reduced frequency of defecation, no defecation for a long time and other symptoms, you need to go to the gastroenterology department of the hospital in a timely manner, but also to the hospital’s Department of Traditional Chinese Medicine.