The normal value for Cytokeratin 19 Fragment should be less than 3.3ng/mL.
Cytokeratin 19 fragments are formed when cells in the lungs undergo apoptosis during metabolism, which leads to the degradation of keratin substances within the cells. Apoptosis occurs in normal cells, and an increase in the number of cytokeratin 19 fragments is often indicative of abnormalities in the organism. It indicates that the cell metabolism is accelerated and the probability of cell mutation increases, increasing the risk of cancer.
Cytokeratin 19 fragment is commonly used in oncology or respiratory medicine and has an important role in cancer detection. It is commonly used as a marker for lung cancer, especially squamous epithelial cell carcinoma. Patients are advised to go to regular hospitals for examination and if cytokeratin 19 fragment is detected, the possibility of having lung cancer needs to be suspected.
Further examination should be done under the supervision of a doctor to clarify whether it is lung cancer. If the diagnosis is confirmed, treatment should be carried out actively.