1, Hepatitis B virus carriers, once a year; but those who have a history of hepatitis activity (onset), or have obvious clinical symptoms (fatigue, nausea, dysgeusia, jaundice, wasting, etc.), or those who have alcoholism and a family history of cirrhosis or liver cancer, or those who are middle-aged or older, should be reviewed once every 3-6 months. 2. For patients with hepatitis B under treatment, the examination interval should be decided by the treating physician according to the need. 3, the examination is preferred to liver function (transaminases, bilirubin, protein and other seven items), HBVDNA quantification and B ultrasound test, and if necessary, other items such as liver fibrosis four items and cancer indicators (AFP, CEA), etc. There are about 20 million patients with chronic hepatitis B in China, most of whom need treatment. In particular, 1/3 of them may develop cirrhosis within 15 years, and a significant portion of the latter may develop into hepatocellular carcinoma. Clinical data have confirmed that liver fibrosis progresses rapidly in the early stages of hepatitis B cirrhosis, which is the time to treat it urgently. Therefore, it is important to detect and treat the problem in a timely manner.