Early pregnancy stomach pain like menstrual cramps may be a pre-eclampsia, may also be ectopic pregnancy, acute appendicitis and other diseases caused by the need for specific causes to take medication, surgical treatment. 1. Pre-eclampsia: common symptoms include vaginal bleeding and lower abdominal pain. Patients need to follow the doctor’s instructions to apply progesterone, micronized progesterone and other progesterone drugs. If conservative treatment is ineffective, early pregnancy need to consider the operation. 2. Ectopic pregnancy: mainly manifested as menopause, abdominal pain, vaginal bleeding. For pregnant women with no active intra-abdominal bleeding and no embryo heartbeat, methotrexate should be applied as prescribed by the doctor. For the patients who are not effective in drug treatment and the ectopic pregnancy is serious, they need to consider surgical treatment such as tubectomy and salpingo-oophorectomy. 3. Acute appendicitis: typical symptoms include abdominal pain, nausea and vomiting. For patients with undiagnosed acute appendicitis, antibiotics such as ceftriaxone sodium and metronidazole should be applied as prescribed by the doctor, and antibiotics should also be applied to patients 60 minutes before surgery. For patients who are in early pregnancy, laparoscopic surgery can be considered. Clinical causes of stomach pain in early pregnancy like menstrual cramps in women are more, need to go to the hospital, clear the specific causes and then cooperate with the doctor for treatment.