Eczema on hands and feet is mainly treated with medication and kept away from triggering factors. 1. Medication: If there is no blistering and oozing, you can apply glycerine lotion, tretinoin cream, etc. If there is more oozing, you can use berberine hydrochloride solution and boric acid solution to apply wet compresses. If there is more exudation, you can use berberine hydrochloride solution and boric acid solution to apply wet compresses, and then apply hormone cream after the exudation is reduced. If there is erosion, but not much exudation, zinc oxide oil can be applied. When the itching is severe, you can take anti-allergic drugs such as oral isoprinosine and chlorpheniramine maleate, and you can also take calcium gluconate and vitamin C orally or intravenously to relieve the inflammatory reaction. 2. Keep away from triggering factors: keep hands and feet clean and hygienic, don’t get wet for a long time; pay attention to controlling the room temperature, choose cotton socks and loose shoes; pay attention to keep the mood happy, avoid negative emotions such as tension, anxiety and anger. The same disease, the patient’s physical condition is different, different stages of the disease, treatment methods are different, should be standardized treatment under the guidance of the doctor. All of the above drugs should be used as prescribed by the doctor.