For the patient’s blood test hepatitis B three systems, if the results of the three systems indicate a major triple-positive, the patient is considered more likely to have hepatitis B virus infection through vertical transmission from mother to child. In this case, if the patient’s blood is drawn for liver function, if there is no elevation of glutathione and glutamic oxalacetic aminotransferase, and if the blood is drawn for hepatitis B DNA suggesting that the virus is not replicating, it is recommended to continue to observe the situation and pay attention not to drink alcohol, stay up late or work hard. For some patients, if the hepatitis B DNA indicates that the virus has replicated, and the patient’s liver function is elevated, the patient is considered to be in the window period of virus replication. Patients need to actively carry out antiviral treatment, you can consider oral antiviral drugs, such as entecavir, tenofovir, can also consider injections of interferon for active treatment. For patients with mild liver fibrosis combined with chronic viral hepatitis B viral replication, long-term medication should be considered, and generally cannot be discontinued, which may cause a rebound in viral replication, in addition to a dramatic decline in liver function. For patients who inject interferon, they need to be injected for about six months to a year.