Muscle throbbing in tardive dyskinesia is characterized by involuntary muscle throbbing accompanied by muscle atrophy. Tardive dyskinesia refers to amyotrophic lateral sclerosis. Muscle flutter is caused by damage to the anterior horn cells of the spinal cord and neuronal cells in the brainstem, resulting in involuntary muscle flutter in the skeletal, tongue, and chewing muscles in the corresponding innervated areas. Involuntary muscle twitching is a relatively common and typical clinical symptom of motor neuron disease. It is most common in the tongue muscle, limb skeletal muscle, facial muscle is relatively rare, and extraocular muscle is generally not involved. At the same time, it is often accompanied by the atrophy of the corresponding muscles, and it is easy to induce muscle throbbing after forceful contraction. When the symptoms of amyotrophic lateral sclerosis muscle throbbing are obvious, it is recommended to go to the neurology department of regular hospitals in a timely manner, under the guidance of a professional physician to carry out standardized drug treatment, and assisted by rehabilitation, acupuncture and physiotherapy in order to maximize the delay in the progress of the disease.