Patients wake up with soft legs and weakness, the following reasons are common: First, serious cervical spondylosis: elderly patients with a long history of cervical spine disease, if not treated in time, can be constantly aggravated, resulting in cervical spinal stenosis, cervical disc protrusion, compression of the cervical spinal cord nerve, the patient will wake up with clinical symptoms of soft legs and weakness, and even can not walk normally, through early surgical treatment to lift the nerve compression. If the treatment time is affected, the function of the lower limbs may be completely destroyed. Second, lumbar disc herniation: After the patient has an acute attack of lumbar disc herniation, it can also stimulate the nerves and make the muscles of lower limbs lose innervation, resulting in clinical symptoms of soft and weak legs when waking up from sleep, and can be accompanied by lumbar pain and limited lumbar spine activities. Early diagnosis and treatment can improve clinical symptoms; if diagnosis and treatment are delayed, it may lead to serious adverse consequences and affect the normal life of patients.