Uric acid is the end product of purine metabolism, mainly produced by the cellular metabolic breakdown of nucleic acids and other purine-like compounds and purines in food by the action of enzymes. Uric acid can be derived from the body or from the breakdown of purines in food. The liver is the main site of uric acid production, a small portion can be broken down in the liver or excreted with bile, and most is excreted in the urine. Ninety percent of uric acid is reabsorbed back into the bloodstream in the renal tubules, and its concentration is affected by glomerular filtration and reabsorption. Clinical elevation of uric acid is seen in glomerular filtration impairment and abnormal increase of uric acid production in the body, such as primary gout and secondary gout. Decreased uric acid is seen in renal tubular reabsorption dysfunction and liver function impairment, such as acute hepatic necrosis. When doing a uric acid test it is recommended to avoid a high purine diet for the first 3 days to rule out interference from exogenous uric acid and to ensure the accuracy of the results. When the uric acid test results appear abnormal, you need to go to the hospital in time, follow the doctor’s instructions to standardize the treatment, so as not to delay the condition.