Radical liver cancer surgery refers to the surgical resection of liver tumor, which is one of the common ways to treat liver cancer and is widely used in the clinical treatment of liver cancer. The so-called radical liver cancer surgery is the complete resection of liver cancer through surgery. If the patient’s liver can tolerate the resection after preoperative evaluation, the remaining liver can be fully compensated after the corresponding lesion is resected. Clinically, it currently consists of two main options: open resection as well as minimally invasive resection. The operative modalities include segmental hepatectomy, lobectomy, hemihepatectomy, and so on. Through surgical resection, try to ensure clean resection at one time, which needs to be handled under the comprehensive judgment of clinicians. Radical hepatectomy for liver cancer needs to be judged comprehensively with the patient’s own physical condition as well as the tumor condition, and liver function needs to be closely monitored, and standardized treatment needs to be carried out under the guidance of clinicians, so as to avoid causing serious liver function damage.